Mechanics of soft fibrous living tissues and related fibrous biomaterials

Now available : replay of the meeting inter-GDRs MECAFIB/MECABIO/Réparer l'Humain (streaming)

The next MECAFIB days will focus on the mechanics of soft fibrous living tissues and related fibrous biomaterials. They are co-organised together with the GDR MECABIO and Réparer l'Humain.
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Knowing and understanding the mechanical properties of soft tissues in living organisms constitutes a major scientific challenge and a prerequisite for innovations in health and medical fields. The mechanical function of many of these tissues is (in the first order) dictated by their multi-scale and complex fibrous (passive or active) structure. They respond to physico-chemical interactions modifying their mechanical properties over short periods of time (muscle contraction, fluid-structure interactions, etc.). They also exhibit a biochemical activity affecting their geometry, their nano and microstuctural arrangement and their overall mechanical properties (growth, tissue ageing, etc.) over longer periods of time. This complexity therefore constitutes a source of multiple scientific challenges regarding: (i) suitable methods for in vivo or ex vivo characterization of these tissues at the relevant spatial scales (milli, micro and nanometric), (ii) techniques for modeling their structure-mechanics relationship, as well as their inter or intra-individual variability and their evolution over time.
At the same time, and because of such a complexity in living materials, new fibrous biomaterials are being developed - generally based on a biomimicry approach - and are opening the door to therapeutic advances. The same scientific questions related to the characterisation and the structural and mechanical modelling are therefore a milestone toward their development. These questions are associated with issues related to the synthesis, elaboration and shaping of these biomaterials.

In this context, the aim of this workshop is to review the latest developments tackling these challenges, and to share ideas and advances especially in the following topics:
  • Imaging Techniques for biological fibrous tissues
  • Multiscale mechanical behaviour of these tissues
  • Multiphysical couplings in these media
  • Fibrous biomaterials and biomimicry
These two half-days of workshop are co-organised by the French GDRs (research groups) Mecafib, Mecabio and Réparer l'Humain, in order to gather and confront the approaches developed within these different communities and to strengthen or create new opportunities for collaborations.
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Mis à jour le 15 December 2020